

2022-a time span that includes waves of both Delta and Omicron variants-the booster was 91% effective at protecting against hospitalization in the first two months after people received it, but dropped to 78% four months after the shot. Recent data published by the CDC, for example show that protection against hospitalization for COVID-19 waned even after a booster dose of either the Pfizer-BioNTech or Moderna vaccines.

On one hand, there are troubling signs that the immunity provided by the vaccines is starting to wane, which could make people more vulnerable to COVID-19’s more severe effects. and Israel, that don’t paint a definitive picture about whether an additional dose is necessary for most people. In authorizing a fourth shot, the FDA considered still-emerging data, from both the U.S. “It may be that the decision is made that rather than vaccines we currently have against the virus, we will move to a vaccine that is either against one of the variants-whether that’s Omicron, Beta, or Delta-or that is a mix.” What we know about the efficacy of a fourth shot

“I don’t want to shock anyone, but there may be a need for people to get an additional booster in the fall,” Marks said.
